The golden channel in indirect Dark Matter searches is generally given by prompt gamma-rays produced in the annihilation or decay of the DM particles. However, other complementary signatures can offer similar or better sensitivity to the DM signal, like synchrotron and Inverse Compton radiation from e+e- produced by DM, or the intensity of the gamma-ray anisotropies expected from the DM clustering properties. In the talk I will focus on these signatures and summarize the current constraints and future prospects for DM detection.